in-vitro antimicrobial activities of some iranian conifers

نویسندگان

maryam afsharzadeh department of pharmacodynamic and toxicology, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran.

mahboobe naderinasab department of microbiology, faculty of medicine, mashhad, university of medical science, mashhad iran.

zahra tayarani najaran department of pharmacodynamic and toxicology, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran.

mohammad barzin department of pharmacognosy, faculty of pharmacy, mashhad, university of medical science, mashhad, iran.

چکیده

male and female leaves and fruits of eleven different taxons of iranian conifers (cupressus sempervirens var. horizontalis, c. sempervirens var. sempervirens, c. sempervirens cv. cereifeormis, juniperus communis subsp. hemisphaerica, j. excelsa subsp. excelsa, j. excelsa subsp. polycarpos, j. foetidissima, j. oblonga, j. sabina, platycladus orientalis and taxus baccata) were collected from different localities of iran, dried and extracted with methanol. the extracts were tested for their antimicrobial activity against pseudomonas aeruginosa, staphylococcus aureus, escherichia coli and candida albicans. the extracts were screened qualitatively using four different methods, the disc diffusion, hole plate, cylinder agar diffusion and agar dilution methods, whereas the minimum inhibitory concentrations (mic) of each extract were determined by the agar dilution method. the best result was obtained by means of hole plate method in qualitative determination of antimicrobial activities of extracts and the greatest activity was found against s. aureus in all tested methods.

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عنوان ژورنال:
the iranian journal of pharmaceutical research

جلد ۱۲، شماره ۱، صفحات ۶۳-۷۴

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